The Science
How BuzzClear® works
Enzymes—the key to rapid alcohol metabolisation
Enzyme 1 - Alcohol Dehydrogenase
Alcohol dehydrogenase turns alcohol into aldehyde. Aldehyde is a toxic substance. The accumulation of aldehyde is what causes hangovers and Asian flush.
Enzyme 2 - Aldehyde Dehydrogenase
Aldehyde dehydrogenase turns aldehyde into acetate, a harmless compound that is broken down naturally into carbon dioxide and water.
Containing both enzymes in a patented ratio, BuzzClear® directly accelerates your body’s breakdown of alcohol.
Alcohol is absorbed in different parts of the human body
BUZZCLEAR® works in the small intestine.
BUZZCLEAR®'s carefully formulated enzyme ratio is developed for optimising alcohol breakdown and preventing aldehyde buildup.
The benefits of BUZZCLEAR®
Metabolising faster is better than fixing later
When it comes to enjoying your drinks, it pays to be proactive. BUZZCLEAR® is the only dual-enzyme pre-alcohol supplement on the market so instead of suppressing the unpleasant side effects of a few drinks, it prevents them from happening at all. Not only do you feel better, but it’s better for your body.
While you drink
- Faster alcohol breakdown
- Reduced Asian glow
- Prevents rapid heart beat
- Reduced liver workload
After you drink
- Reduces dizziness and light-headedness
- Sleep better
- Prevents headaches
- Reduces vomiting
Long-term
- Reduced risk of alcohol-related liver disease
- Reduced risk of alcohol-related cancers
- May lower alcohol-related Alzheimers risk
- Reduced risk of heart disease
Patent
Alcolear holds three US patents for its unique dual-enzyme supplement and is seeking patents in key areas around the globe. These patents cover a composition containing two enzymes working together to efficiently break down alcohol in the human body. The first enzyme converts alcohol into a harmful metabolite, which is then converted by the second enzyme into a harmless form that can be excreted from the body. The specific ratio of these enzymes in the composition is crucial for avoiding elevated levels of the intermediate harmful metabolite, ensuring optimal alcohol metabolism and minimising negative symptoms.
Publication
BUZZCLEAR® is proven to rapidly digest alcohol and completely prevent aldehyde accumulation.
Animal testing conducted by one of the universities in Hong Kong has yielded extremely positive results.
Seto SW et al. Acceleration of Ethanol Metabolism by a Patented Bos taurus Isolated Alcohol Degradation Protein (ADP) on Acute Alcohol Consumption. Foods. 2024;13(19).
Academic Studies
Asians with ALDH2 gene variants are more susceptible to alcohol hangovers, even at lower alcohol consumption levels.
Genetic variations in alcohol-metabolising enzymes, particularly in Asian populations, can influence hangover susceptibility and severity. Specifically, individuals of Asian descent with ALDH2*2 alleles, which are variants of the aldehyde dehydrogenase gene, may experience slower breakdown of acetaldehyde, causing more severe hangovers and are more likely to experience hangovers at lower levels of alcohol consumption compared to those without this genetic variation.
Containing effective aldehyde dehydrogenase enzymes, BUZZCLEAR® provides effective enzymes to people with ALDH2*2 alleles and reduces or eliminates hangover effects.
Medicine and supplements containing turmeric or curcumin - risk of liver injury
Some Hangover pills might contain turmeric or curcumin as active ingredients. In 2023, The Australian Government’s Therapeutic Goods Administration (TGA) has issued a safety advisory warning that people with liver problem should avoid medicine and supplements containing Curcuma species and/or curcumin.
BUZZCLEAR® is free from turmeric or curcumin, ensuring safe use.
Science backed solutions, developed by leading scientist
Dr Wong Bing Lou - Chief Scientist
Dr Wong is a biotechnology innovator, inventor of BUZZCLEAR®, and renowned enzyme expert. As Acting Director at the New England Enzyme Centre (today Genzyme NASDAQ: GENZ), he supported the creation of Cerezyme. As one of founding members of Biopure (NASDAQ: BPUR) he was responsible for the development of antibiotics and artificial bloods Hemopure®️ and Oxyglobin®️. His mission has always been to make life better through the expert application of science.
